ELISA RAN anti-
Quantity:100µg
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle(By similarity). The complex with BIRC5/ survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecµLe TPX2 to microtubµLes. Acts as a negative regµLator of the kinase activity of VRK1 and VRK2. Enhances AR-mediated transactivation. Transactivation decreases as the poly-Gln length within AR increases.
Immunogen:RAN, member RAS oncogene family
Synonyms:ARA24
Observed MW:24 kDa
Uniprot ID:P62826
Reactivity:, Mouse, Rat
Tested Application:ELISA, IHC, IF, IP, WB
Recommended dilution:WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Gene ID:5901
Research Area:Epigenetics, Signal Transduction, Metabolism
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