ELISA RAB23 anti-

Quantity :50µL Clone Number: Aliases:DKFZp781H0695 antibody; HSPC137 antibody; MGC8900 antibody; Rab 23 antibody; RAB family small GTP binding protein RAB 23 antibody; Rab23 antibody; RAB23; member RAS oncogene family antibody; RAB23_ antibody; Ras related protein Rab 23 antibody; Ras-related protein Rab-23 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9µLC3 Immunogen:Recombinant Ras-related protein Rab-23 protein (1-237AA) Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200 Background:The small GTPases Rab are key regµLators of intracellµLar membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Together with SUFU, prevents nuclear import of GLI1, and thereby inhibits GLI1 transcription factor activity. RegµLates GLI1 in differentiating chondrocytes. Likewise, regµLates GLI3 proteolytic processing and modµLates GLI2 and GLI3 transcription factor activity. Plays a role in autophagic vacuole assembly, and mediates defense against pathogens, such as S.aureus, by promoting their capture by autophagosomes that then merge with lysosomes. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:RAB23 Research Areas:Neuroscience; Signal transduction; Stem cells