ELISA DCC anti-

Quantity :50µL Clone Number: Aliases:Colorectal cancer related chromosome sequence 18 antibody; Colorectal cancer suppressor antibody; CRC 18 antibody; CRC18 antibody; CRCR 1 antibody; CRCR1 antibody; DCC antibody; DCC_ antibody; Deleted in colorectal cancer protein antibody; Deleted in colorectal carcinoma antibody; ImmunoglobµLin superfamily DCC subclass member 1 antibody; Netrin receptor DCC antibody; Tumor suppressor protein DCC antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P43146 Immunogen:Synthetic peptide of DCC Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:50-1:200 Background:This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobµLin superfamily of cell adhesion molecµLes, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregµLated in colorectal cancer and esophageal carcinoma. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:DCC Research Areas:Epigenetics and Nuclear Signaling?Neuroscience?Cancer;Cell biology