ELISA GEMIN6 Antibody, FITC

Quantity :50µg Clone Number: Aliases:FLJ23459 antibody; Gem (nuclear organelle) associated protein 6 antibody; Gem-associated protein 6 antibody; GEMI6 antibody; GEMI6_ antibody; Gemin 6 antibody; Gemin-6 antibody; Gemin6 antibody; SIP2 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q8WXD5 Immunogen:Recombinant Gem-associated protein 6 protein (1-167AA) Raised in:Rabbit Reactivity: Tested Applications: Background:The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellµLar pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:FITC Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:GEMIN6 Research Areas:Epigenetics and Nuclear Signaling