ELISA MCAM anti-

Quantity :50µL Clone Number: Aliases:A32 antigen antibody; CD 146 antibody; CD146 antibody; CD146 antigen antibody; Cell surface glycoprotein MUC18 antibody; Cell surface glycoprotein P1H12 antibody; Gicerin antibody; Mcam antibody; Melanoma adhesion molecµLe antibody; Melanoma associated antigen A32 antibody; Melanoma associated antigen MUC18 antibody; Melanoma associated glycoprotein MUC18 antibody; Melanoma cell adhesion molecµLe antibody; Melanoma-associated antigen A32 antibody; Melanoma-associated antigen MUC18 antibody; MelCAM antibody; MUC 18 antibody; MUC18 antibody; MUC18_ antibody; S endo 1 antibody; S endo 1 endothelial associated antigen antibody; S-endo 1 endothelial-associated antigen antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P43121 Immunogen:Synthetic peptide of MCAM Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB, IHC; ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:100-1:300 Background:CD146 (cluster of differentiation 146) also known as the melanoma cell adhesion molecµLe (MCAM) or cell surface glycoprotein MUC18, is a 113kDa cell adhesion molecµLe currently used as a marker for endothelial cell lineage. In s, the CD146 protein is encoded by the MCAM gene. Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellµLar junctions in vascµLar tissue. Its expression may allow melanoma cells to interact with cellµLar elements of the vascµLar system, thereby enhancing hematogeneous tumor spread. CoµLd be an adhesion molecµLe active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellµLar calcium concentration. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:MCAM Research Areas:Cancer?CardiovascµLar;Immunology;Signal transduction?Stem cells