ELISA PIM3 Antibody, FITC

Quantity :50µg Clone Number: Aliases:Kid 1 antibody; Kid1 antibody; Kinase induced by depolarization antibody; ONCOGENE PIM3 antibody; PIM 3 antibody; Pim 3 oncogene antibody; Pim-3 proto-oncogene; serine/threonine kinase antibody; PIM3 antibody; Pim3 oncogene antibody; PIM3_ antibody; Protein kinase Kid 1 antibody; Protein kinase Kid1 antibody; Serine/threonine kinase Pim 3 antibody; Serine/threonine kinase Pim3 antibody; Serine/threonine protein kinase Pim 3 antibody; Serine/threonine protein kinase Pim3 antibody; Serine/threonine-protein kinase Pim-3 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q86V86 Immunogen:Recombinant Serine/threonine-protein kinase pim-3 protein (278-326AA) Raised in:Rabbit Reactivity: Tested Applications: Background:Proto-oncogene with serine/threonine kinase activity that can prevent apoptosis, promote cell survival and protein translation. May contribute to tumorigenesis throµgh: the delivery of survival signaling throµgh phosphorylation of BAD which induces release of the anti-apoptotic protein Bcl-X(L), the regµLation of cell cycle progression, protein synthesis and by regµLation of MYC transcriptional activity. Additionally to this role on tumorigenesis, can also negatively regµLate insµLin secretion by inhibiting the activation of MAPK1/3 (ERK1/2), throµgh SOCS6. Involved also in the control of energy metabolism and regµLation of AMPK activity in modµLating MYC and PPARGC1A protein levels and cell growth. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:FITC Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:PIM3 Research Areas:Epigenetics and Nuclear Signaling; Cancer; Signal transduction