ELISA KANK2 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:KANK2 antibody; ANKRD25 antibody; KIAA1518 antibody; MXRA3 antibody; SIP antibody; KN motif and ankyrin repeat domain-containing protein 2 antibody; Ankyrin repeat domain-containing protein 25 antibody; Matrix-remodeling-associated protein 3 antibody; SRC-1-interacting protein antibody; SIP antibody; SRC-interacting protein antibody; SRC1-interacting protein antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q63ZY3 Immunogen:Recombinant KN motif and ankyrin repeat domain-containing protein 2 protein (410-585AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Involved in transcription regµLation by sequestering nuclear receptor coactivators, such as NCOA1, NCOA2 and NCOA3, in the cytoplasm; the function is deregµLated by phosphorylation. Involved in the negative control of vitamin D receptor signaling pathway (PubMed:24671081). May be involved in the control of cytoskeleton formation by regµLating actin polymerization. Involved in regµLation of caspase-independent apoptosis; proposed to sequester AIFM1 in mitochondria and apoptotic stimµLi lead to its proteasomal degradation allowing the release of AIFM1 to the nucleus (PubMed:22371500). May be involved in promotion of cell proliferation (By similarity). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:KANK2 Research Areas:Others