ELISA KLHL12 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:C3IP1 antibody; CµL3 interacting protein 1 antibody; CµL3-interacting protein 1 antibody; DKIR antibody; DKIR homolog antibody; FLJ27152 antibody; hDKIR antibody; Kelch like 12 (Drosophila) antibody; Kelch like 12 antibody; Kelch like 12 variant antibody; Kelch like protein 12 antibody; Kelch like protein C3IP1 antibody; kelch-like family member 12 antibody; Kelch-like protein 12 antibody; KLH12_ antibody; KLHL 12 antibody; klhl12 antibody; OTTHUMP00000038799 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q53G59 Immunogen:Recombinant Kelch-like protein 12 protein (1-220AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Substrate-specific adapter of a BCR (BTB-CµL3-RBX1) E3 ubiquitin ligase complex that acts as a negative regµLator of Wnt signaling pathway and ER-Golgi transport. The BCR(KLHL12) complex is involved in ER-Golgi transport by regµLating the Quantity of COPII coats, thereby playing a key role in collagen export, which is required for embryonic stem (ES) cells division: BCR(KLHL12) acts by mediating monoubiquitination of SEC31 (SEC31A or SEC31B). As part of the BCR(KLHL12) complex, also acts as a negative regµLator of the Wnt signaling pathway by mediating ubiquitination and subsequent proteolysis of DVL3. The BCR(KLHL12) complex also mediates polyubiquitination of DRD4, without leading to degradation of DRD4. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:KLHL12 Research Areas:Others