ELISA Phospho-PAK7|PAK6 (Ser602|Ser560) anti-

Quantity :100µL Clone Number: Aliases:EC 2.7.11.1 antibody; KIAA1264 antibody; MGC26232 antibody; p21 activated kinase 7 antibody; p21 protein (Cdc42/Rac)-activated kinase 7 antibody; p21(CDKN1A) activated kinase 7 antibody; p21-activated kinase 5 antibody; p21-activated kinase 7 antibody; PAK 5 antibody; PAK 7 antibody; PAK-5 antibody; PAK-7 antibody; PAK5 antibody; PAK7 antibody; PAK7_ antibody; Protein kinase PAK5 antibody; Serine/threonine protein kinase PAK 7 antibody; Serine/threonine-protein kinase PAK 7 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9P286 Immunogen:Peptide sequence around phosphorylation site of Serine 602/560(R-K-S(p)-L-V) derived from PAK5/6. Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, WB; WB:1:500-1:1000 Background: This gene encodes a protein that shares a high degree of sequence similarity with p21-activated kinase (PAK) family members. The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases, characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. PAK kinases are implicated in the regµLation of a number of cellµLar processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. The protein encoded by this gene was found to interact with androgen receptor (AR), which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development. Yang F., J. Biol. Chem. 276:15345-15353(2001). Wagner T., Submitted (FEB-1999) to the EMBL/GenBank/DDBJ databases. Sjoeblom T., Science 314:268-274(2006). Clonality:Polyclonal Isotype:IgG Purification Method:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjµgates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:PAK5/PAK6 Research Areas:Neuroscience;Cell biology;Signal transduction