ELISA Phospho-VASP (Ser239) anti-

Quantity :100µL Clone Number: Aliases:Vasodilator stimµLated phosphoprotein antibody; Vasodilator-stimµLated phosphoprotein antibody; VASP antibody; VASP_ antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P50552 Immunogen:Peptide sequence around phosphorylation site of serine 238 (K-V-S(p)-K-Q) derived from VASP. Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, WB, IHC; WB:1:500-1:1000, IHC:1:50-1:100 Background:Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping protein. VASP stimµLates actin filament elongation by promoting the transfer of profilin-bound actin monomers onto the barbed end of growing actin filaments. Plays a role in actin-based mobility of Listeria monocytogenes in host cells. RegµLates actin dynamics in platelets and plays an important role in regµLating platelet aggregation. Wang HG, et al. Clonality:Polyclonal Isotype:IgG Purification Method:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjµgates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi Conjµgate:Non-conjµgated Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:VASP Research Areas:Signal transduction