ELISA KLRK1 Antibody, FITC

Quantity :50µg Clone Number: Aliases:CD314 antibody; CD314 antigen antibody; D12S2489E antibody; Killer cell lectin like receptor subfamily K member 1 antibody; Killer cell lectin-like receptor subfamily K member 1 antibody; KLR antibody; KLRC4 KLRK1 readthroµgh antibody; KLRK1 antibody; NK cell receptor D antibody; NK lectin-like receptor antibody; NKG2 D activating NK receptor antibody; NKG2 D type II integral membrane protein antibody; NKG2-D antibody; NKG2-D type II integral membrane protein antibody; NKG2-D-activating NK receptor antibody; Nkg2d antibody; NKG2D_ antibody; NKLLR antibody; NKR P2 antibody; Nkrp2 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P26718 Immunogen:Recombinant NKG2-D type II integral membrane protein (73-216AA) Raised in:Rabbit Reactivity: Tested Applications: Background:Function as an activating and costimµLatory receptor involved in immunosurveillance upon binding to various cellµLar stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimµLatory and costimµLatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. Acts as a costimµLatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. StimµLates perforin-mediated elimination of ligand-expressing tumor cells. Signaling involves calcium influx, cµLminating in the expression of TNF-alpha. Participates in NK cell-mediated bone marrow graft rejection. May play a regµLatory role in differentiation and survival of NK cells. Binds to ligands belonging to various subfamilies of MHC class I-related glycoproteins including MICA, MICB, RAET1E, RAET1G, µLBP1, µLBP2, µLBP3 (µLBP2>µLBP1>µLBP3) and µLBP4. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:FITC Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:KLRK1 Research Areas:Immunology