ELISA CHD1 anti-

Quantity :50µL Clone Number: Aliases:ATP dependent helicase CHD 1 antibody; ATP-dependent helicase CHD1 antibody; CHD 1 antibody; CHD-1 antibody; Chd1 antibody; CHD1_ antibody; Chromodomain helicase DNA binding protein 1 antibody; Chromodomain-helicase-DNA-binding protein 1 antibody; DKFZp686E2337 antibody; OTTHUMP00000222625 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O14646 Immunogen:Recombinant Chromodomain-helicase-DNA-binding protein 1 protein (1501-1710AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC, ChIP; Recommended dilution: IHC:1:20-1:200 Background:ATP-dependent chromatin-remodeling factor which functions as substrate recognition component of the transcription regµLatory histone acetylation (HAT) complex SAGA. RegµLates polymerase II transcription. Also required for efficient transcription by RNA polymerase I, and more specifically the polymerase I transcription termination step. RegµLates negatively DNA replication. Not only involved in transcription-related chromatin-remodeling, but also required to maintain a specific chromatin configuration across the genome. Is also associated with histone deacetylase (HDAC) activity (By similarity). Required for the bridging of SNF2, the FACT complex, the PAF complex as well as the U2 snRNP complex to H3K4me3. Functions to modµLate the efficiency of pre-mRNA splicing in part throµgh physical bridging of spliceosomal components to H3K4me3. Required for maintaining open chromatin and pluripotency in embryonic stem cells. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CHD1 Research Areas:Epigenetics and Nuclear Signaling