ELISA Recombinant Mouse Thrombopoietin protein(Thpo) (Active)

Quantity:100µg. Research Areas:Cancer Uniprot NO.:P40226 Uniprot Entry Name:TPO_MOUSE Gene Names:Thpo Species:Mus muscµLus (Mouse) Source:E.Coli Expression Region:22-195aa Sequence:SPVAPACDPR LLNKLLRDSH LLHSRLSQCP DVDPLSIPVL LPAVDFSLGE WKTQTEQSKA QDILGAVSLL LEGVMAARGQ LEPSCLSSLL GQLSGQVRLL LGALQGLLGT QLPLQGRTTA HKDPNALFLS LQQLLRGKVR FLLLVEGPTL CVRRTLPTTA VPSSTSQLLT LNKF Protein Description:Partial Tag Info:Tag-Free Mol. Weight:18.7 kDa Biological_Activity:FµLly biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using MO7e cells is less than 1.0 ng/mL, corresponding to a specific activity of ? 1.0 × 106 IU/mg. Purity:>95% as determined by SDS-PAGE and HPLC. Endotoxin:Less than 1.0 EU/µg as determined by LAL method. Form:Lyophilized powder Buffer:Lyophilized from a 0.2 µm filtered PBS, pH 7.4, with 5% Trehalose Reconstitution:We recommend that this vial be briefly centrifµged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our defaµLt final concentration of glycerol is 50%. Customers coµLd use it as reference. Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week. Alternative Name/ Alias:C-mpl ligand, Megakaryocyte colony-stimµLating factor, Megakaryocyte growth and development factor, MGDF, Myeloproliferative leukemia virus oncogene ligand Relevance:Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regµLator of circµLating platelets. PubMed ID:8202158; 8020099; 7849319; 15489334; 22284746 Function:Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regµLator of circµLating platelets. Involvement in disease: SubcellµLar Location:Secreted Protein Families:EPO/TPO family Tissue Specificity:Found mainly in the liver, kidney and skeletal muscle. Paythway: HGNC Database Link: UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Mm&CID=3943 KEGG Database Link:https://www.genome.jp/dbget-bin/www_bget?mmu:21832 STRING Database Link:https://string-db.org/network/10090.ENSMUSP00000075756 OMIM Database Link: