ELISA APEX1 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.) Background:Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecµLes by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in cells. Splice variants have been found for this gene; all encode the same protein. Immunogen:APEX nuclease (mµLtifunctional DNA repair enzyme) 1 Synonyms:APE, APE1, APEX, APX, HAP1, REF1 Observed MW:39 kDa Uniprot ID:P27695 Reactivity: Tested Application:ELISA, WB, IP, IF Recommended dilution:WB: 1:500 - 1:2000; IF: 1:50 - 1:100; IP: 1:50 - 1:200 Gene ID:328 Research Area:CardiovascµLar, Metabolism