ELISA REC8 anti-

Quantity :100µL Clone Number: Aliases:Cohesin Rec8p antibody; homolog of rad21 S. pombe antibody; Meiotic recombination and sister chromatid cohesion phosphoprotein of the rad21p family antibody; Meiotic recombination protein REC8 homolog antibody; Meiotic recombination protein REC8-like 1 antibody; rec8 antibody; REC8 homolog (yeast) antibody; REC8 like 1 antibody; REC8_ antibody; Rec8p antibody; Recombination and sister chromatid cohesion protein homolog antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O95072 Immunogen:SyntheQuantityd peptide derived from internal of REC8. Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB; WB:1:500-1:3000 Background:Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II By similarity. Parisi S., Mol. Cell. Biol. 19:3515-3528(1999). Ota T., Nat. Genet. 36:40-45(2004). Ebert L., Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases. Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:REC8 Research Areas:Epigenetics and Nuclear Signaling;Cell biology