ELISA PARD3 anti-

Quantity :100µL Clone Number: Aliases:agouti signaling protein antibody; ASIP antibody; Atypical PKC isotype specific interacting protein antibody; Atypical PKC isotype-specific-interacting protein antibody; Baz antibody; bazooka antibody; CoagµLation factor II receptor-like 2 antibody; CTCL tumor antigen se2-5 antibody; F2rl2 antibody; PAR-3 antibody; par-3 family cell polarity regµLator alpha antibody; par-3 family cell polarity regµLator antibody; PAR3 alpha antibody; par3 antibody; PAR3-alpha antibody; PARD-3 antibody; Pard3 antibody; PARD3_ antibody; PARD3A antibody; Partitioning defective 3 homolog antibody; Partitioning-defective 3 homolog antibody; Partitioning-defective protein 3; C. elegans; homolog of antibody; SE2-5L16 antibody; SE2-5LT1 antibody; SE2-5T2 antibody; Thrombin receptor-like 2 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q8TEW0 Immunogen:SyntheQuantityd peptide derived from internal of PARD3. Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB, IF; WB:1:500-1:3000, IF:1:100-1:500 Background:Adapter protein involved in asymmetrical cell division and cell polarization processes. Seems to play a central role in the formation of epithelial tight junctions. Targets the phosphatase PTEN to cell junctions By similarity. Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Required for establishment of neuronal polarity and normal axon formation in cµLtured hippocampal neurons. Joberty G., Nat. Cell Biol. 2:531-539(2000). Fang C.M., Cell Res. 11:223-229(2001). Kohjima M., Biochem. Biophys. Res. Commun. 299:641-646(2002). Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:PARD3 Research Areas:Neuroscience;Signal transduction