ELISA HIPK3 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:Androgen receptor interacting nuclear protein kinase antibody; Androgen receptor-interacting nuclear protein kinase antibody; ANPK antibody; DYRK6 antibody; Fas interacting serine/threonine protein kinase antibody; Fas-interacting serine/threonine-protein kinase antibody; FIST antibody; FIST3 antibody; Hipk3 antibody; HIPK3_ antibody; homeodomain interacting protein kinase 3 antibody; Homeodomain-interacting protein kinase 3 antibody; Homolog of protein kinase YAK1 antibody; PKY antibody; RP24 297H17.5 antibody; YAK1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9H422 Immunogen:Recombinant Homeodomain-interacting protein kinase 3 protein (841-1130AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Serine/threonine-protein kinase involved in transcription regµLation, apoptosis and steroidogenic gene expression. Phosphorylates JUN and RUNX2. Seems to negatively regµLate apoptosis by promoting FADD phosphorylation. Enhances androgen receptor-mediated transcription. May act as a transcriptional corepressor for NK homeodomain transcription factors. The phosphorylation of NR5A1 activates SF1 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimµLation. In osteoblasts, supports transcription activation: phosphorylates RUNX2 that synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:HIPK3 Research Areas:Epigenetics and Nuclear Signaling; Cell biology; Signal transduction