ELISA FKBP8 Antibody, HRP

Quantity :50µg Clone Number: Aliases:38 kDa FK506-binding protein antibody; 38 kDa FKBP antibody; 38kDa antibody; FK506 binding protein 8 antibody; FK506 binding protein 8, 38kDa antibody; FK506 binding protein, 38kDa antibody; FK506-binding protein 8 antibody; FKBP 38 antibody; FKBP-38 antibody; FKBP-8 antibody; Fkbp8 antibody; FKBP8_ antibody; FKBPR38 antibody; hFKBP38 antibody; Peptidyl-prolyl cis-trans isomerase FKBP8 antibody; PPIase FKBP8 antibody; Rotamase antibody; Sam11 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q14318 Immunogen:Recombinant Peptidyl-prolyl cis-trans isomerase FKBP8 protein (58-190AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Constitutively inactive PPiase, which becomes active when bound to calmodµLin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modµLates its phosphorylation state. The BCL2/FKBP8/calmodµLin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regµLation of apoptosis. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:FKBP8 Research Areas:Cell biology; Signal transduction