ELISA Phospho-REL (Ser503) anti-

Quantity :100µL Clone Number: Aliases:Avian reticµLoendotheliosis antibody; C REL antibody; C Rel protein antibody; c Rel proto oncogene protein antibody; Oncogene REL antibody; Oncogene REL avian reticµLoendotheliosis antibody; Proto-oncogene c-Rel antibody; REL antibody; REL_ antibody; v rel avian reticµLoendotheliosis viral oncogene homolog antibody; v rel reticµLoendotheliosis viral oncogene homolog antibody; V rel reticµLoendotheliosis viral oncogene homolog (avian) antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q04864 Immunogen:Peptide sequence around phosphorylation site of serine 503 (T-S-S(p)-D-S) derived from Rel. Raised in:Rabbit Reactivity: Tested Applications:ELISA, IF; IF:1:100-1:200 Background:The REL gene encodes c-Rel, a transcription factor that is a member of the Rel/NFKB family, which also includes RELA (MIM 164014), RELB (604758), NFKB1 (MIM 164011), and NFKB2 (MIM 164012). These proteins are related throµgh a highly conserved N-terminal region termed the 'Rel domain,' which is responsible for DNA binding, dimerization, nuclear localization, and binding to the NFKB inhibitor (MIM 164008) (Belguise and Sonenshein, 2007 (PubMed 18037997)). Baeuerle, P.A. and Henkel, T. (1994) Annu Rev Immunol 12, 141-79. Baeuerle, P.A. and Baltimore, D. (1996) Cell 87, 13-20. Haskill, S. et al. (1991) Cell 65, 1281-9. Thompson, J.E. et al. (1995) Cell 80, 573-82. Clonality:Polyclonal Isotype:IgG Purification Method:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjµgates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi Conjµgate:Non-conjµgated Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:REL Research Areas:Epigenetics and Nuclear Signaling;Cancer;Signal transduction