ELISA RPS6KB1 (Ab-421) anti-

Quantity :100µL Clone Number: Aliases:70 kDa ribosomal protein S6 kinase 1 antibody; KS6B1_ antibody; p70 alpha antibody; P70 beta 1 antibody; p70 ribosomal S6 kinase alpha antibody; p70 ribosomal S6 kinase beta 1 antibody; p70 S6 kinase alpha antibody; P70 S6 Kinase antibody; p70 S6 kinase; alpha 1 antibody; p70 S6 kinase; alpha 2 antibody; p70 S6K antibody; p70 S6K-alpha antibody; p70 S6KA antibody; p70(S6K) alpha antibody; p70(S6K)-alpha antibody; p70-alpha antibody; p70-S6K 1 antibody; p70-S6K antibody; P70S6K antibody; P70S6K1 antibody; p70S6Kb antibody; PS6K antibody; Ribosomal protein S6 kinase 70kDa polypeptide 1 antibody; Ribosomal protein S6 kinase beta 1 antibody; Ribosomal protein S6 kinase beta-1 antibody; Ribosomal protein S6 kinase I antibody; RPS6KB1 antibody; S6K antibody; S6K-beta-1 antibody; S6K1 antibody; Serine/threonine kinase 14 alpha antibody; Serine/threonine-protein kinase 14A antibody; STK14A antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P23443 Immunogen:Peptide sequence around aa.419~423 (P-R-T-P-V) derived from p70 S6 Kinase. Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB, IHC; WB:1:500-1:1000, IHC:1:50-1:200 Background:Phosphorylates specifically ribosomal protein S6 in response to insµLin or several classes of mitogens. Promotes protein synthesis by phosphorylating PDCD4 at 'Ser-67' and targeting it for degradation. Xiao-Feng, et al. (2003) Le1 30 Volume 22: 484-497 An WL, et al. (2003) Am J Pathol. 163(2): 591-607. Le XF, et al. (2003) Oncogene.22(4): 484-97 Clonality:Polyclonal Isotype:IgG Purification Method:Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjµgates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. Conjµgate:Non-conjµgated Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:RPS6KB1 Research Areas:Epigenetics and Nuclear Signaling;Cell biology;Metabolism;Signal transduction