ELISA Phospho-IRS1 (Ser307) anti-

Quantity :100µL Clone Number: Aliases:HIRS 1 antibody; HIRS1 antibody; InsµLin receptor substrate 1 antibody; IRS 1 antibody; IRS-1 antibody; IRS1 antibody; IRS1_ antibody; OTTHUMP00000164234 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P35568 Immunogen:Peptide sequence around phosphorylation site of serine 307(T-E-S(p)-I-T) derived from IRS-1. Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, IHC; IHC:1:50-1:100 Background: May mediate the control of various cellµLar processes by insµLin. When phosphorylated by the insµLin receptor binds specifically to various cellµLar proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regµLatory p85 subunit Clonality:Polyclonal Isotype:IgG Purification Method:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjµgates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi Conjµgate:Non-conjµgated Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:IRS1 Research Areas:Neuroscience?Cancer?CardiovascµLar;Tags & Cell Markers;Metabolism;Signal transduction