ELISA TRIAP1 anti-

Quantity :50µL Clone Number: Aliases:p53-inducible cell-survival factor antibody; p53CSV antibody; Protein 15E1.1 antibody; TP53-regµLated inhibitor of apoptosis 1 antibody; TRIA1_ antibody; Triap1 antibody; WF 1 antibody; WF1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O43715 Immunogen:Recombinant TP53-regµLated inhibitor of apoptosis 1 protein (1-76AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200 Background:Involved in the modµLation of the mitochondrial apoptotic pathway by ensuring the accumµLation of cardiolipin (CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane (PubMed:23931759). Likewise, the TRIAP1:PRELID3A complex mediates the transfer of phosphatidic acid (PA) between liposomes (in vitro) and probably functions as a PA transporter across the mitochondrion intermembrane space (in vivo) (PubMed:26071602). Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis (PubMed:15735003). Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:TRIAP1 Research Areas:Others