ELISA RNF212 anti-

Quantity :50µL Clone Number: Aliases:FLJ38841 antibody; Hypothetical protein LOC285498 antibody; LOC285498 antibody; OTTHUMP00000147525 antibody; Probable E3 SUMO-protein ligase RNF212 antibody; RING finger protein 212 antibody; RN212_ antibody; RNF 212 antibody; RNF212 antibody; ZHP3 antibody; ZHP3; C. elegans; homolog of antibody; ZIP3-related protein antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q495C1 Immunogen:Recombinant Probable E3 SUMO-protein ligase RNF212 protein (1-297AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200 Background:SUMO E3 ligase that acts as a regµLator of crossing-over during meiosis: required to couple chromosome synapsis to the formation of crossover-specific recombination complexes. Localizes to recombination sites and stabilizes meiosis-specific recombination factors, such as MutS-gamma complex proteins (MSH4 and MSH5) and TEX11. May mediate sumoylation of target proteins MSH4 and/or MSH5, leading to enhance their binding to recombination sites. Acts as a limiting factor for crossover designation and/or reinforcement and plays an antagonist role with CCNB1IP1/HEI10 in the regµLation of meiotic recombination (By similarity). Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:RNF212 Research Areas:Epigenetics and Nuclear Signaling