ELISA NCR3 Antibody, HRP

Quantity :50µg Clone Number: Aliases:1C7 antibody; Activating natural killer receptor p30 antibody; Activating NK A1 receptor antibody; CD337 antibody; CD337 antigen antibody; LY117 antibody; Lymphocyte antigen 117 antibody; MALS antibody; Natural cytotoxicity triggering receptor 3 antibody; Natural killer cell p30 related protein antibody; Natural killer cell p30-related protein antibody; Ncr3 antibody; NCTR3_ antibody; NK-p30 antibody; NKp30 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O14931 Immunogen:Recombinant Natural cytotoxicity triggering receptor 3 protein (19-135AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Cell membrane receptor of natural killer/NK cells that is activated by binding of extracellµLar ligands including BAG6 and NCR3LG1. StimµLates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also promotes myeloid dendritic cells (DC) maturation, both throµgh killing DCs that did not acquire a mature phenotype, and inducing the release by NK cells of TNFA and IFNG which promote DC maturation. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:NCR3 Research Areas:Immunology; Stem cells