ELISA FAM3B anti-

Quantity :50µL Clone Number: Aliases:2-21 antibody; C21orf11 antibody; C21orf76 antibody; Cytokine like protein 2 21 antibody; Cytokine-like protein 2-21 antibody; Fam3b antibody; FAM3B_ antibody; Family with sequence similarity 3 member B antibody; ORF9 antibody; Pancreatic-derived factor antibody; PANDER antibody; PRED44 antibody; Protein FAM3B antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P58499 Immunogen:Fusion protein of FAM3B Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:50-1:200 Background:FAM3B (family with sequence similarity 3, member B), also known as ORF9, C21orf11 or PANDER, is a 235 amino acid secreted protein that localizes to discrete vesicµLar and perinuclear structures. Expressed at high levels in pancreas and at lower levels in kidney, colon, testis, prostate and small intestine, FAM3B functions as an islet-specific cytokine that promotes apoptosis and may inhibit InsµLin secretion from beta-cells, possibly playing a role in overall pancreatic activity. FAM3B shares 78% sequence identity with its mouse counterpart, sµggesting a conserved role between species. Three isoforms of FAM3B, designated A, B and C, exist due to alternative splicing events. The gene encoding FAM3B maps to chromosome 21, which houses approximately 300 genes and comprises nearly 1.5% of the genome. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:FAM3B Research Areas:Immunology?Metabolism