ELISA NCK1 anti-

Quantity :50µL Clone Number: Aliases:Cytoplasmic protein NCK1 antibody; Melanoma Nck protein antibody; MGC12668 antibody; NCK 1 antibody; NCK adaptor protein 1 antibody; NCK alpha antibody; NCK antibody; NCK tyrosine kinase antibody; Nck-1 antibody; NCK1 antibody; NCK1_ antibody; NCKalpha antibody; Non catalytic region of tyrosine kinase antibody; SH2/SH3 adaptor protein NCK alpha antibody; SH2/SH3 adaptor protein NCK-alpha antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P16333 Immunogen:Recombinant Cytoplasmic protein NCK1 protein (58-377AA) Raised in:Rabbit Reactivity:, Rat Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200 Background:Adapter protein which associates with tyrosine-phosphorylated growth factor receptors, such as KDR and PDGFRB, or their cellµLar substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in the DNA damage response, not in the detection of the damage by ATM/ATR, but for efficient activation of downstream effectors, such as that of CHEK2. Plays a role in ELK1-dependent transcriptional activation in response to activated Ras signaling. ModµLates the activation of EIF2AK2/PKR by dsRNA. May play a role in cell adhesion and migration throµgh interaction with ephrin receptors. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:NCK1 Research Areas:Epigenetics and Nuclear Signaling; Cancer; Signal transduction