ELISA MAP3K11 anti-
Quantity :50µg
Clone Number:
Aliases:2610017K16Rik antibody; EC 2.7.11.25 antibody; M3K11_ antibody; Map3k11 antibody; MEKK11 antibody; MGC17114 antibody; Mitogen-activated protein kinase kinase kinase 11 antibody; Mixed lineage kinase 3 antibody; Mixed lineage protein kinase 3 antibody; mLk-3 antibody; mLk3 antibody; Protein tyrosine kinase PTK1 antibody; PTK1 antibody; RHOE antibody; SH3 domain containing proline rich kinase antibody; SPRK antibody; Src-homology 3 domain-containing proline-rich kinase antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:Q16584
Immunogen:Recombinant Mitogen-activated protein kinase kinase kinase 11 protein (536-693AA)
Raised in:Rabbit
Reactivity:
Tested Applications:ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200
Background:Activates the JUN N-terminal pathway. Required for serum-stimµLated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), MAPK3 (ERK) and MAPK8 (JNK1) throµgh phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7. Plays a role in mitogen-stimµLated phosphorylation and activation of BRAF, but does not phosphorylate BRAF directly. Influences microtubµLe organization during the cell cycle.
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjµgate:Non-conjµgated
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:MAP3K11
Research Areas:Signal transduction
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