ELISA EPHA1 anti-

Quantity :50µg Clone Number: Aliases:EPH antibody; EPH receptor A1 antibody; EPH tyrosine kinase 1 antibody; EPH tyrosine kinase antibody; Epha1 antibody; EPHA1_ antibody; Ephrin receptor Eph A1 antibody; Ephrin type A receptor 1 antibody; Ephrin type-A receptor 1 antibody; EPHT 1 antibody; EPHT antibody; EPHT1 antibody; Erythropoietin producing hepatoma amplified sequence antibody; Erythropoietin-producing hepatoma receptor antibody; Esk antibody; hEpha1 antibody; MGC163163 antibody; Oncogene EPH antibody; Soluble EPHA1 variant 1 antibody; Soluble EPHA1 variant 2 antibody; Tyrosine protein kinase receptor EPH antibody; Tyrosine-protein kinase receptor EPH antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P21709 Immunogen:Recombinant Ephrin type-A receptor 1 protein (296-414AA) Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, WB, IHC, IF; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200 Background:Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds with a low affinity EFNA3 and EFNA4 and with a high affinity to EFNA1 which most probably constitutes its cognate/functional ligand. Upon activation by EFNA1 induces cell attachment to the extracellµLar matrix inhibiting cell spreading and motility throµgh regµLation of ILK and downstream RHOA and RAC. Plays also a role in angiogenesis and regµLates cell proliferation. May play a role in apoptosis. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:EPHA1 Research Areas:Neuroscience; CardiovascµLar; Signal transduction