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ELISA Recombinant Draxin(DRAXIN)

https://biotrend.labm.com/web/image/product.template/132115/image_1920?unique=4d171d3
Quantity: 200µg. Other Quantitys are also available. Please Inquire. In Stock: No Lead time: 10-20 working days Research Topic: Neuroscience Uniprot ID: Q8NBI3 Gene Names: DRAXIN Organism: Homo sapiens () AA Sequence: GALAPGTPARNLPENHIDLPGPALWTPQASHHRRRGPGKKEWGPGLPSQAQDGAVVTATRQASRLPEAEGLLPEQSPAGLLQDKDLLLGLALPYPEKENRPPGWERTRKRSREHKRRRDRLRLHQGRALVRGPSSLMKKAELSEAQVLDAAMEESSTSLAPTMFFLTTFEAAPATEESLILPVTSLRPQQAQPRSDGEVMPTLDMALFDWTDYEDLKPDGWPSAKKKEKHRGKLSSDGNETSPAEGEPCDHHQDCLPGTCCDLREHLCTPHNRGLNNKCFDDCMCVEGLRCYAKFHRNRRVTRRKGRCVEPETANGDQGSFINV Expression Region: 26-349aa Sequence Info: FµLl Length Source: E.coli Tag Info: N-terminal 6xHis-SUMO-tagged MW: 52 kDa Alternative Name(s): Dorsal inhibitory axon guidance protein Dorsal repµLsive axon guidance protein Neucrin Relevance: ChemorepµLsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepµLsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. Reference: "Neucrin is a novel neural-specific secreted antagonist to canonical Wnt signaling."Miyake A., Takahashi Y., Miwa H., Shimada A., Konishi M., Itoh N.Biochem. Biophys. Res. Commun. 390:1051-1055(2009) Purity: Greater than 90% as determined by SDS-PAGE. Storage Buffer: Tris-based buffer,50% glycerol Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃. Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

907,00 € 907.0 EUR 907,00 €

907,00 €

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