ELISA MBTPS1 anti-

Quantity :50µL Clone Number: Aliases:MBTPS1 antibody; KIAA0091 antibody; S1P antibody; SKI1Membrane-bound transcription factor site-1 protease antibody; EC 3.4.21.112 antibody; Endopeptidase S1P antibody; Subtilisin/kexin-isozyme 1 antibody; SKI-1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q14703 Immunogen:Recombinant Membrane-bound transcription factor site-1 protease protein (803-1052AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200 Background:Serine protease that catalyzes the first step in the proteolytic activation of the sterol regµLatory element-binding proteins (SREBPs). Other known substrates are BDNF, GNPTAB and ATF6. Cleaves after hydrophobic or small residues, provided that Arg or Lys is in position P4. Cleaves known substrates after Arg-Ser-Val-Leu (SERBP-2), Arg-His-Leu-Leu (ATF6), Arg-Gly-Leu-Thr (BDNF) and its own propeptide after Arg-Arg-Leu-Leu. Mediates the protein cleavage of GNPTAB into subunit alpha and beta, thereby participating in biogenesis of lysosomes. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:MBTPS1 Research Areas:Epigenetics and Nuclear Signaling; Cell biology; Metabolism; Signal transduction